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Certain MTHFR mutations may also elevate homocysteine. Homocysteine is an am

ino acid linked to a wide range of health concerns, including a risk factor for inflammation, heart disease, pregnancy-related complications, mental health issues, behavioral problems in children, and an impaired ability to detoxify or remove wastes.

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One of the genetic factors involves point mutations in the methylenetetrahyd

rofolate reductase (MTHFR) gene (OMIM 607093). Thermolabile variants of the MTHFR enzyme are mildly deficient at reducing 5,10-methylenetetrahydrofolate to 5-methylenetetrahydrofolate, a cofactor in the remethylation of homocysteine to methionine.

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What is the MTHFR test? T he MTHFR test or methylenetetrahydrofolate reducta

se test has become extremely popular due to a number of alternative medicine practitioners promoting it as the source of many chronic illnesses. But is it something you should worry about? This test is basically looking for two types of genetic mutations known as C677T and A1298C that affect the MTHFR enzyme involved ...

In my Part I of MTHFR mutations, I discussed what they are, why they matter,

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FREE SHIPPING. Our MTHFR Home Test Kits test the two most important genes: M

THFR C677T and MTHFR A1298C. A simple cheek swab. Safe for men, women and children of all ages… even babies. Purchase as many as you want for friends and family. We do not sell or share your results with any third party or insurance company for any reason.

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This test looks for mutations in the MTHFR gene. The MTHFR gene helps breaks

down an amino acid called homocysteine. If there is a mutation, homocysteine can build up in the body and cause a variety of health problems. Learn more.

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MTHFR Testing – A1298C has not been found clinically to have an effect in

homocysteine levels. This allele has a greater effect in the production of BH4 (tetrahydrobiopterin). BH4 is a cofactor in the production of neurotransmitters such as epinephrine, serotonin, L-Dopa, melatonin, etc.

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If one parent passes on an MTHFR gene with a mutation, the child will get a

heterozygous MTHFR mutation. If both parents pass on the mutation, the child will have a homozygous mutation. 1 Two of the main types of MTHFR mutations (also known as “variants”) are called C677T and A129BC.

My Doctor ordered MTHFR, DNA Analysis test from LabCorp and it was negative

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The MTHFR gene also helps your body convert an amino acid known as homocyste

ine into another very important type of amino acid known as methionine. You need methionine for your body to make proteins. 1 The process by which MTHFR helps produce folate and methionine is known as methylation.

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Having an MTHFR gene variation is basically like having a typo in the gene t

hat tells the enzyme how to function. The enzyme will still work, but its activity is compromised to only provide 65% to as little as 30% of its normal function. MTHFR variations are especially common among Hispanics, Caucasians and Asians.

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